Is conservative treatment (enucleation using modified Carnoy’s solution) of odontogenic keratocyst in the maxilla good prognosis?
전우영, 박정호, 구정귀, 백진아, 고승오,
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전우영 ( Jeon Woo-Young ) -
박정호 ( Park Jung-Ho ) -
구정귀 ( Ku Jeong-Kui ) - Jeonbuk National University School of Dentistry Department of Oral and Maxillofacial Surgery
백진아 ( Baek Jin-A ) -
고승오 ( Ko Seung-O ) -
Abstract
Odontogenic keratocysts (OKCs) located in the maxillae have rarely been reported in the literature. Standard treatment modalities for OKC range from marsupialization to marginal resection. However, most of the studies on OKC treatment have been related to mandibular OKCs. The anatomical structure and loose bone density of the maxillae and the empty space of the maxillary sinus could allow rapid growth of a lesion and the ability to tolerate tumor occupancy in the entire maxilla within a short period of time. Therefore, OKCs of the maxillae require more aggressive surgery, such as resection. As an alternative, this report introduces a modified Carnoy’s solution, a strong acid, as an adjuvant chemotherapy after cyst enucleation. This report describes the clinical outcomes of enucleation using a modified Carnoy’s solution in patients with large OKCs on the posterior maxillae. In three cases, application of a modified Carnoy’s solution had few side effects or morbidity. Each patient was followed for four to six years, and none showed any signs of recurrence. In conclusion, adjuvant treatment with a modified Carnoy’s solution can be considered a treatment option capable of reducing the recurrence rate of OKC in the maxillae.
키워드
Adjuvant chemotherapy; Odontogenic cysts; Prognosis
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